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A new way to regulate the leakiness of blood vessels by blocking TGF beta surrounding blood vessels in mice can enhance delivery of molecular imaging agents and drugs to tumors, according to research published in the March online issue of Disease Models and Mechanisms.
For patients with high-risk, potentially operable rectal cancer, therapy with preoperative chemotherapy prior to standard chemoradiation and surgical resection is a reasonable treatment with acceptable safety and promising long-term outcomes, based on a study published in the March issue of the Lancet Oncology.
In a study evaluating the use of induction chemotherapy followed by radiation for larynx preservation in head and neck cancer patients, researchers of the Bretonneau Hospital in Tours, France found that half of patients reported no trouble eating or swallowing and most had a low-risk of voice disability after procedure, according to a presentation Feb. 25 at the Multidisciplinary Head and Neck Cancer (MHNC) Symposium.
Pre-treatment maximal standardized uptake value (SUVmax) from FDG PET imaging of the primary tumor in head and neck squamous cell carcinoma patients is a strong predictor of prognosis, while pre-treatment SUVmax of the lymphadenopathy is significantly associated with distant metastasis, according to a study presented on Feb. 26 at the Multidisciplinary Head and Neck Cancer Symposium in Chandler, Ariz.
Surgery without subsequent radiotherapy offers reasonable overall survival outcomes for patients suffering from stage I small cell lung cancer (SCLC), according to the results of a recent study published in the February edition of the Journal of Thoracic Oncology.
The U.S. Patent and Trademark Office has issued Cleveland BioLabs a patent titled "Modulating Apoptosis" covering the method of protecting humans from radiation using flagellin or its derivatives, including CBLB502.
Research published in the Dec. 2 issue of the Journal of the American Medical Association suggests that criteria based on CT imaging of changes in tumors from colorectal liver metastases after chemotherapy with the drug bevacizumab (Avastin, Genentech/Roche) may have the potential to predict overall survival.
The Centers for Medicare & Medicaid Services (CMS) will allow reimbursement for Spectrum Pharmaceuticals radiotherapeutic antibody Zevalin (ibritumomab tiuxetan) for the treatment of patients with previously untreated follicular non-Hodgkin's lymphoma.
The use of chemotherapy concurrently with radiotherapy for patients with advanced head and neck cancer (who haven’t undergone previous surgery) reduces disease recurrence, the development of new tumors and death, according to a study published online Oct. 27 in the Lancet Oncology.
Bioluminescence imaging can help in the early detection of eye cancer, according to a study published online, ahead of the December issue of Investigative Ophthalmology & Visual Science.
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PET/CT may help identify patients with disseminated seminoma that was not detected by CT scan, according to a study presented last week at the 2010 Genitourinary Cancers Symposium (ASCO-GU) in San Francisco.
Proton beam radiation therapy showed encouraging results for patients with locally advanced sinonasal malignancies, according to a study presented Feb.25 at the Multidisciplinary Head and Neck Cancer Symposium in Chandler, Ariz.
Use of an abridged radiation therapy could reduce the amounts of chemotherapy and toxicity in patients with advanced head and neck cancers, according to a study presented by Phuc Felix Nguyen-Tan, MD, Feb. 26 at the Multidisciplinary Head and Neck Cancer symposium.
A new technique called personalized analysis of rearranged ends provides an accurate and specific way to monitor tumors by identifying personalized biomarkers from tumor DNA, according to a study published in the Feb. 24 issue of Science Translational Medicine.
Women with cervical cancer who are treated with chemoradiotherapy, as opposed to radiotherapy alone, presented higher survival rates and have a greater likelihood their cancer will not spread to other parts of the body or return at all, according to a study published Jan. 19 in the Cochrane Database of Systematic Reviews and conducted by the Chemoradiotherapy for Cervical Cancer Meta-analysis Collaboration.
Research published in this month’s issue of Cancer suggests that early FDG-PET imaging during preoperative chemotherapy could identify patients with estrogen receptor-positive breast cancer tumors who will not respond optimally to preoperative chemotherapy.
Radiation therapy and chemotherapy given before prostatectomy is safe and may have the potential to reduce cancer recurrence and improve patient survival, based on study findings presented this week at the 2009 American Society of Radiology Oncology (ASTRO) conference in Chicago.
Simultaneous use of chemotherapy and high-dose radiotherapy has produced encouraging results in the treatment of limited-stage small-cell lung cancer, according to a phase II study presented Tuesday at the 2009 American Society for Radiation Oncology (ASTRO) meeting in Chicago.
The U.S. guidelines for the treatment of brain metastases were released Monday at the 2009 Congress of Neurological Surgeons' meeting in New Orleans.
Although noncardiac incidental findings are common on cardiac CT (CCT) scans, clinically significant or indeterminate incidental findings are less prevalent; however, investigation of incidental findings is not without cost or risk, according to study results published in the Oct. 13 issue of the Journal of the American College of Cardiology.
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