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When added to MRI, gadolinium-based contrast agents were found to substantially enhance the malignancy criteria for primary tumor visualization, as well as increase the accuracy in the detection of lymph node metastases, according to a meta-analysis published in the February edition of the Journal of the National Cancer Institute.
After years of research regarding gadolinium-based contrast agents used during MRI being linked to the skin disease nephrogenic systemic fibrosis (NSF), the FDA has found the greatest risk in GE Healthcare’s Omniscan, Bayer HealthCare's Magnevist and Covidien’s Optimark.
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Acute adverse reactions from gadolinium-based contrast agents used during MRI to help improve the information seen on the images rarely occur, according to a study published in the February issue of the American Journal of Roentgenology.
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