CT laser mammography improves detection in dense breasts
Imaging Diagnostic Systems Inc. (IMDS), provider of laser optical breast imaging systems, released study results indicating the advantages of using CT laser breast imaging as an adjunct to conventional mammography to improve detection of occult cancers in dense breasts.

“These CTLM [CT laser mammography] results are being released as a response to the growing number of requests for performance statistics received from distributors and prospective customers worldwide. The results were obtained from our initial PMA-designed clinical study,” said Tim Hansen, IMDS CEO.
 
“The findings are quite positive,” said Eric Milne, MD, IMDS director of clinical research. “The study, from four sites in North America, involving 705 breasts of 515 patients, biopsied in 451 cases, was scientifically rigorous. It demonstrated that, in a dense breast population, the adjunctive use of CTLM, classifying DCIS as malignant, increased sensitivity from 50.0 to 58.3 percent over mammography alone and improved specificity from 75.5 to 86.8 percent. When DCIS is classified as pre-malignant, the figures changed slightly, increasing sensitivity from 43.8 to 56.2 percent over mammography alone and improving specificity from 73.6 to 84.4 percent. The difference between the two sets of results reflects, we believe, that the pathologically ‘benign’ form of DCIS shows angiogenesis in only 30 percent of cases, whereas comedocarcinoma shows angiogenesis in 75 percent, an observation that that might prove useful for stratifying DCIS for treatment purposes. One of the more remarkable results of using CTLM as an adjunct was that specificity also improved along with sensitivity, reducing the negative biopsy rate.”
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