MICAD adds 11 agents

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The Molecular Imaging and Contrast Agent Database (MICAD) has uploaded 11 agents.

The PET agents are:

  • [11C]DPA-713  and [18F]PBR06, which both targets peripheral benzodiazepine receptor (PBR), also known as translocator protein (TSPO)
  • [18F]AV-45, which targets ß-amyloid peptide
  • [18F]FB-RMSH, which targets melanocortin-1 (MC-1) receptor (MC1R)

The SPECT agents are:

  • 123I-Nicotinamide, which targets gastrin/cholecystokinin-2 receptor (CCK-2R)
  • 99mTc-HYNIC-cyclo-MG1, which targets gastrin/cholecystokinin-2 receptor (CCK-2R)

The MRI agents are:

  • Gd-DOTA-R832, which targets vascular cell adhesion molecule-1 (VCAM-1)
  • Gd-DTPA-g-R826, which targets phosphatidylserine
  • USPIO-PHO, which targets ß-amyloid peptide
  • VCAM-1-PFC-19mF which targets vascular cell adhesion molecule-1 (VCAM-1)

The optical agent is:

  • Avas12a1-IRDye800, which targets vascular endothelial growth factor receptor-2 (VEGFR-2)

The MICAD database currently lists 805 agents and is developed by the National Center for Biotechnology Information at the National Institutes of Health.