New PET agent could be a versatile clot catcher

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German researchers have shown that a new small-molecule radiotracer can work with PET, and PET alone, to image blood clots in multiple anatomic regions and regardless of where they formed.

Their preclinical study is running in the July edition of the Journal of Nuclear Medicine and is nicely summarized in a news item posted by SNMMI’s communications department.

“Currently available diagnostic techniques of thrombus [blood clot] imaging rely on different modalities depending on the vascular territory,” study co-author Andrew Stephens, MD, PhD, of Piramal Imaging GmbH in Germany says in the item.

SNMMI says the new, fast-clearing tracer— 18F-GP1—ably detected small venous and arterial clots, plus endothelial damage and emboli in the brain, in a primate trial.

Click here to read the full study and below for the SNMMI news item.