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Dynamic contrast agent enhanced MRI (DCE MRI) is a fairly well-established technique that was first introduced in the early 1990s. Used in the pharmaceutical and clinical research environments, the post-processing algorithm evaluates dynamic images to measure contrast agent uptake in target tissue. 

SPECT is far from the new kid on the molecular imaging block, but except for cardiac imaging, this nuclear medicine modality has not yet realized routine clinical utility as a replacement for conventional planar scanning. Recently developed reconstruction protocols and hybrid SPECT/CT scanners, however, could breathe new life into SPECT by opening the door to clinically feasible whole-body SPECT/CT. The University of Texas M.D. Anderson Cancer Center in Houston, is at the cutting edge of SPECT/CT research. This month, M.D. Anderson experts, Chair of Nuclear Medicine , Associate Professor , and Senior Medical Physicist Bill Erwin from the department of Imaging Physics discuss the clinical path to and potential of whole-body SPECT/CT.

PET/CT has come a long way since Time magazine awarded the scanner one of its Medical Inventions of the Year award in December 2000.

Higher quality images and shorter acquisition times than stand-alone PET systems are among the benefits of adding 64-slice CT.

Numerous clinical studies have compellingly demonstrated that FDG-PET generally outperforms not only individual diagnostic tests, but also a combination of tests to diagnose and stage many cancers. Physicians and patients need to be informed.

Over the last decade, hybrid imaging has become a standard of care in radiology, cardiology, nuclear medicine and oncology. Integrated scanning systems offer a number of advantages for physicians and patients.

PET/CT has come a long way since Time magazine awarded the scanner one of its Medical Inventions of the Year award in December 2000. Published literature since 1996 has established strong evidence for the advantages of PET/CT over PET and CT alone for characterizing lesions as malignant or benign, and for staging, restaging and therapy monitoring of cancer. In addition, emerging applications include imaging of cardiovascular diseases and infection.

The ease of using one software program to evaluate images from different time points is key to more accurate cancer staging at PET/CT-Zentrum Hamburg in Germany.

Crouse Hospital in Syracuse, N.Y., is a 566-bed, acute-care community hospital committed to superior patient care. Its commitment to the community is paralleled by a strong collaborative relationship between its radiology and nuclear medicine departments. 

Torsten Kuwert, MD, of the University of Erlangen, details how new techniques in SPECT/CT are gaining wider acceptance in diagnosing and staging indeterminate bone lesions—in a single patient visit.

Ready to take PET scanning to the next level in its debut this month, high-definition PET (HD•PET) scans optimize image uniformity and enable visualization of smaller structures.

Molecular imaging is providing new insights into human physiology and disease. It provides more accurate diagnosis, cancer staging, restaging and treatment monitoring, and allows for highly accurate determinations of cardiac and brain function. Molecular imaging thus enables more appropriate and timely treatment decisions.