NIH awards Indiana researcher $44.7M for early onset Alzheimer’s study using imaging

Liana Apostolova, MD, a researcher at the Indiana University School of Medicine, has won a five-year $44.7 million research grant from the National Institutes of Health (NIH) to study early-onset Alzheimer's disease with MRI and PET imaging, according to an Oct. 4 report by the Indianapolis Business Journal.  

“It’s frustrating to us as researchers because we still don’t understand all the mechanisms of Alzheimer’s disease and our treatments that have tried and failed,” Apostolova told IBJ.  

The multi-institutional study will involve 400 early-onset Alzheimer's patients who have mild cognitive impairment or mild Alzheimer’s disease with PET scans that showed buildup of beta amyloid protein in the brain.  

Along with 100 healthy control participants, these patients will also undergo cognitive testing, MRI and PET scans, the collection of spinal fluid and DNA testing at yearly intervals for the next three years.  

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