Molecular Imaging

The Department of Energy’s Nuclear Security Administration (NNSA) has chosen four U.S. companies to begin negotiations with in an effort to produce Molybdenum-99 (Mo-99) without the use of highly enriched uranium.

A novel PET/CT imaging agent—18F-GP1—produced a high-quality image and yielded a high detection rate for diagnosing acute venous thromboembolism (VTE), reported researchers of a study featured in the February issue of The Journal of Nuclear Medicine.

Stereotactic ablative body radiation therapy (SABR) nearly doubled the overall survival of patients with inoperable stage I lung cancer compared to standard radiotherapy, according to results of a multi-center phase III trial published in the Lancet Oncology.

A molecular imaging technique using PET technology may improve how the efficacy or failure of hormone therapy is measured for breast cancer patients, according to research published online in the February issue of The Journal of Nuclear Medicine

Researchers found that combining iodine-123 metaiodobenzylguanidine (123I-MIBG) SPECT imaging with cardiac MRI helped identify specific subsets of heart tissue more prone to arrhythmia, or an irregular heartbeat, according to research published in the January issue of The Journal of Nuclear Medicine.  

With the help of PET scans, researchers have found women’s brains appear to be three years younger than men’s. The findings, published in Proceedings of the National Academy of Sciences, may explain why women tend to remain mentally sharper longer than men.

A novel MRI approach developed by researchers from Austria showed promise for non-invasively measuring hypoxia and neovascularization in breast tumors, according to a Jan. 24 article published by Physicsworld.

A novel radiotracer tested for the first time in humans may help improve the detection of primary and metastatic melanoma, a highly aggressive form of skin cancer, according to a study published in the January issue of the Journal of Nuclear Medicine.

Radiolabeled 18F-fluoride PET/CT proved superior at detecting bone metastases (BM) than a comparative radiotracer, according to a Jan. 14 study published in Clinical Radiology.

Breast-specific gamma imaging (BSGI) outperformed breast MRI in predicting a complete pathologic response to neoadjuvant chemotherapy (NAC) with breast cancer, according to research published online Jan. 8 in the American Journal of Roentgenology.

The findings suggest the evaluation of molecular biomarkers for Alzheimer’s disease should be adjusted for race, as African American patients were found to have lower levels of tau—a key biomarker used to identify the disease, according to research published online Jan. 7 in JAMA Neurology.

A team of Dutch researchers has developed a real-time hybrid fluoroscopic and nuclear imaging detector that may aid interventional radiology (IR) procedures such as radioembolization, according to authors of a Jan. 8 study published in Radiology.