Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Targeted radiation may help children with chemo-resistant liver cancer

In pediatric patients with chemotherapy-resistant liver cancer, targeted tumor radiation can improve survival or help shrink the tumor to allow for surgery, according to a recent study published in Pediatric Blood and Cancer.

November 14, 2018

AI estimates full-dose PET images from low-dose scans

Deep learning can estimate full-dose PET images from scans with significantly lower dosages, according to a new study in the Journal of Digital Imaging. The method may make performing PET scans safer and more affordable.

November 9, 2018
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Focused ultrasound method releases drugs millimeters from targeted brain areas

Using focused ultrasound, researchers from the Stanford University School of Medicine in California have developed a noninvasive method that helps deliver drugs to within a few millimeters of a targeted area of the brain, according to a study published online Nov. 7 in the journal Neuron.

November 8, 2018
MURR reactor

Missouri reactor establishes only domestic supply of I-131 radioisotope

After more than 30 years, a domestic supply of the radioisotope Iodine-131 (I-131) is now available for diagnostic imaging and thyroid cancer treatment.

November 8, 2018

Researches identify features least-sensitive to PET system variations

Researchers from the Medical University of Vienna in Austria provided new guidance for selecting optimizing features from 18F-FDG-PET/CT studies—demonstrating feature variations can be minimized for selected image parameters and imaging systems, in a new study published Nov. 2 in the Journal of Nuclear Medicine.

November 7, 2018
SNMMI

SNMMI issues alert over expected Mo-99 shortage

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) issued an alert Wednesday, Oct. 31, warning members of an expected shortage of Mo-99 during the first-half of November, according to a news release.

November 1, 2018

Clinical trial involving novel PET agent may help Parkinson’s patients

An upcoming study will test a new imaging agent which allows visualization of human synapses, according to a news release. Results will inform a future trial designed to aid Parkinson’s patients.

October 23, 2018

Communication is key: Nuclear medicine departments fail diabetes patients preparing for 18-FDG PET/CT

Nuclear medicine departments are not communicating proper pre-scan instructions to diabetes mellitus management patients for optimizing fluoride-18 fluorodeoxyglucose (FDG) PET/CT imaging, according to new research published in the Journal of the American College of Radiology.

October 22, 2018

Around the web

"Gen AI can help tackle repetitive tasks and provide insights into massive datasets, saving valuable time," Thomas Kurian, CEO of Google Cloud, said Tuesday. 

SCAI and four other major healthcare organizations signed a joint letter in support of intravascular ultrasound. 

The newly approved AI models are designed to improve the detection of pulmonary embolisms and strokes in patients who undergo CT scans.

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