Fujifilm Life Science of Stamford, Conn., has introduced the LAS-4000, a luminescent image analyzer for multi-spectral Western blotting and expanded fluorescent capabilities for the vivo imaging of small animals.
The LAS-4000 is the latest version in Fujifilm’s LAS line of charge-coupled device (CCD)-based camera systems. Additional light sources, most notably epi-ultraviolet (UV) and epi-near-infrared (IR) illuminators, coupled with in vivo imaging of small animal samples distinguish the LAS-4000 from its predecessor, the LAS-3000.
The UV light source gives researchers the capability to use quantum dots for in vitro applications such as multi-spectral Western blotting. IR capabilities enable deeper penetration of excitation light for high-sensitivity small animal in vivo imaging using longer wavelength fluorochromes, according to the company.
Additional features of the LAS-4000 include six interchangeable light sources, a five-position filter turret and a 3.2 megapixel super CCD imaging chip cooled to -30 degrees Celsius for decreased noise during longer exposures, Fuji said. A Fujinon lens, with an F-stop number of 0.85, can capture images from distances as short as several tens of centimeters. The LAS-4000’s sensitivity has a linear dynamic range up to four orders of magnitude.