Study: MRI bests PET in preoperative detection of prostate cancer

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MRI had a higher sensitivity and accuracy than 11C-choline PET (C-PET) and 18F-fluorodeoxyglucose PET (FDG-PET), according to a study published online April 23 in the Journal of Magnetic Resonance Imaging.

Haruo Watanabe, MD from department of radiology at Gifu University Hospital, Japan, and colleagues obtained C-PET, FDG-PET and MR images from 43 consecutive patients with suspected prostate cancer. In 26 patients prostate cancers were histopathologically confirmed.

PET and MR images were reviewed at random by a nuclear and a genitourinary radiologist retrospectively and assigned a confidence level for the presence of prostate cancer using a four-point scale.

Watanabe and colleagues found that the sensitivity was greater with MR (88 percent) and C-PET (73 percent) images than with FDG-PET images (31 percent). The accuracy was greater with MR images (88 percent) than with C-PET (67 percent) and FDG-PET (53 percent) images.

C-PET and FDG-PET did not improve the detection and MRI should be primarily performed in the preoperative detection of prostate cancer, concluded Watanabe and colleagues.