Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Q&A: Cardiologists explore the potential impact of a screening program for aortic stenosis
We already screen patients for breast cancer and lung cancer on a regular basis. Why not establish screening programs for aortic stenosis?
Multimodality imaging helps cardiologists manage heart failure patients—with an assist from AI
Purvi Parwani, MD, discussed the trend toward multimodality imaging for heart failure management. All modalities have their own weaknesses, she explained.
No echocardiography, no problem? AI evaluates cardiac function using chest X-rays
Researchers think their new AI model could be especially helpful in areas where qualified physicians and/or ultrasound technology are in short supply.
AI-powered platform for heart failure detection gains FDA clearance
According to data submitted to the FDA, the platform has been linked to an accuracy of 90%, sensitivity of 87.8% and specificity of 83%.
Cardiologists and surgeons perform first TAVR using CT imaging guidance on HF patient with blood clot
“We believe this case is potentially groundbreaking," one interventional cardiologist said.

Arzhang Fallahi, MD, and David Hsi, MD, discussing imaging-based aortic stenosis screening

Q&A: Cardiologists explore the potential impact of a screening program for aortic stenosis

We already screen patients for breast cancer and lung cancer on a regular basis. Why not establish screening programs for aortic stenosis?

September 11, 2023

Purvi Parwani, MD, director of echocardiography, Loma Linda University Medical Center, explains the trend where heart failure imaging guidelines are driving a rising use of mixed multimodality imaging. #ASE #ASE2023

Multimodality imaging helps cardiologists manage heart failure patients—with an assist from AI

Purvi Parwani, MD, discussed the trend toward multimodality imaging for heart failure management. All modalities have their own weaknesses, she explained.

September 7, 2023

Artificial intelligence (AI) model using chest x-rays to evaluate cardiac function

No echocardiography, no problem? AI evaluates cardiac function using chest X-rays

Researchers think their new AI model could be especially helpful in areas where qualified physicians and/or ultrasound technology are in short supply.

July 13, 2023

Tablet projecting metaphorical medical hologram

AI-powered platform for heart failure detection gains FDA clearance

According to data submitted to the FDA, the platform has been linked to an accuracy of 90%, sensitivity of 87.8% and specificity of 83%.

December 8, 2022

transcatheter aortic valve replacement (TAVR) procedure guided by CT fusion imaging on a patient with heart failure and a blood clot. CT fusion imaging-guided deployment of the Sentinel Cerebral Protection System during a TAVR procedure. Image courtesy of Vasudev et al.

Cardiologists and surgeons perform first TAVR using CT imaging guidance on HF patient with blood clot

“We believe this case is potentially groundbreaking," one interventional cardiologist said.

May 6, 2022

MRI detects heart failure risk in patients with dilated cardiomyopathy

About 40% of individuals had scarring patterns on their heart muscle visible during imaging, which was associated with a greater risk of suffering a major cardiac event.

July 16, 2020

A new gene-editing therapy has been tested on humans for the first time, resulting in a significant reduction in their low-density lipoprotein (LDL) cholesterol that could potentially last for decades. The study’s authors presented these early results at the AHA 2023 meeting.

Genetic variant linked to chemotherapy-induced cardiomyopathy

The same genetic variants that have been uncovered in patients with two other types of cardiomyopathy are also present in an uncommonly high proportion of people with cancer therapy-induced cardiomyopathy (CCM), researchers reported in Circulation.

April 17, 2019

CDK2 inhibitors protect cancer patients from anthracycline-induced cardiotoxicity

Inhibiting a certain class of cyclin-dependent kinase (CDK) proteins could protect cancer patients from chemotherapy-induced heart failure—the second leading cause of death in the demographic after cancer recurrence—according to research published in the Journal of Biological Chemistry.

November 7, 2018

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