Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Agendia test for molecular subtyping of breast cancer is a better guide to pre-surgical treatment

In findings that could eventually change the way breast cancer is treated, a study reports that the BluePrint genomic test provides more accurate information about the molecular subtype of breast cancer than does conventional IHC-FISH pathology testing.

September 15, 2014

Eli Lilly funds lawsuit against CMS for limiting amyloid imaging

Makers of F-18 florbetapir (Amyvid) are bankrolling a lawsuit against the Centers for Medicare & Medicaid Services (CMS), which hampered coverage of amyloid imaging earlier this year as a means for ruling out Alzheimer’s disease. The lawsuit was filed in federal court by Lilly and others Sept. 5, according to this Wall Street Journal report.

September 15, 2014
analyzing financial data

CMS: Slow growth in U.S. health spending

The Centers for Medicare & Medicaid Services (CMS) has provided projected U.S. healthcare spending for the next several years and it is modest. Due to a timid economy and higher private insurance plan costs that pinch demand for healthcare services, average annual healthcare spending is expected to grow by 5.7 percent this year and just about 6 percent from 2013 to 2023.

September 5, 2014

Agendia announces study showing molecular subtyping can improve breast cancer treatment

In findings that may eventually change the way breast cancer is evaluated and treated, a new study reports that the BluePrint genomic test provides more accurate information about the molecular subtype of a specific breast cancer, compared to the use of conventional IHC-FISH pathology tests.

September 3, 2014

Cancer screening bias casts a shadow on clinical decision making

In the world of cancer screening, there may be a bias of accessibility that is skewed toward more screening when doctors are paid more by Medicaid, according to a study conducted by the division of health services and social policy research at RTI International in Washington, D.C.

August 29, 2014

Novel nanoparticles pull double duty

Researchers from the University of California, Davis, have created dynamic nanoparticles that can be used to both diagnose and treat cancer.

August 28, 2014

Radiant Sage named on CIOReview list of 100 most promising technology companies

Radiant Sage LLC, a provider of on-demand clinical trial imaging infrastructure solutions, today announced that it has been named to CIOReview's list of 100 Most Promising Technology Companies. The CIOReview100 includes companies that are gaining momentum in the technology industry and making an impact.

August 28, 2014

Chronic pain and loss of motivation are chemically intertwined

Chronic pain is associated with a reduction in reward seeking, but not just because people are hurting and do not feel up to the task. New Stanford brain research is providing a more comprehensive picture of how molecular changes in the brain dictate loss of motivation in painful settings.

August 27, 2014

Around the web

Automated AI-generated measurements combined with annotated CT images can improve treatment planning and help referring physicians and patients better understand their disease, explained Sarah Jane Rinehart, MD, director of cardiac imaging with Charleston Area Medical Center.

Two advanced algorithms—one for CAC scores and another for segmenting cardiac chamber volumes—outperformed radiologists when assessing low-dose chest CT scans. 

"Gen AI can help tackle repetitive tasks and provide insights into massive datasets, saving valuable time," Thomas Kurian, CEO of Google Cloud, said Tuesday. 

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