Nuclear Medicine

Nuclear medicine (also called molecular imaging) includes positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. Nuclear imaging is achieved by injecting small amounts of radioactive material (radiopharmaceuticals) into patients before or during their scan. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

thermometer

F-18 FDG PET/CT highly sensitive for diagnosing cause of fevers with unknown origin

Such scans determined the final diagnosis in 54% of patients and were more accurate than CRP and WBC levels for identifying fever origin, according to research published in Scientific Reports.

February 10, 2022
University of Missouri Research Reactor

University's research reactor increases medical isotope production in wake of supply disruption

“Our dedicated staff are committed to getting lifesaving treatments delivered to the patients who need them,” MURR's executive director said in a statement on Feb. 9.

February 9, 2022

Isotope update: Target date for resuming production of Mo-99 still unclear

Production of Lu-177 is expected to resume on Saturday, Feb. 12, but the Mo-99 supply shortage could continue for weeks.

February 8, 2022

Medical isotope update: Shortage expected to last weeks as nuclear reactor remains sidelined

Mo-99, Lu-177, and I-131 supply issues are forecasted until approximately one week after the downed reactor resumes operations on Feb. 12, the Nuclear Medicine Europe Emergency Response Team said.

February 3, 2022

Nuclear reactor in Poland steps up to address Mo-99 shortage

The Maria reactor in Poland began producing the isotope hours after a water leak shut down the high flux reactor in Petter, the Netherlands.

February 1, 2022

Medical isotope shortage looms as 'unplanned' outage halts Mo-99, Lu-177 production

The root cause of the problem has not yet been discovered, halting isotope production for an undisclosed amount of time, according to SNMMI.

January 26, 2022

PSMA-PET validates commonly used system measuring risk of prostate cancer recurrence

"The accuracy of PSMA-PET is essential to improve stratification and potentially outcomes both in low-risk and high-risk settings,” a doctor involved in the study explained in the Journal of Nuclear Medicine.

January 21, 2022
SNMMI images of unusual imaging pattern observed on FDG PET/CT or FDG PET/MR that may be due to Omicron COVID-19 infection. Unlike the FDG PET/CT pattern seen with infections from previous strains of COVID-19, with principal involvement of the lungs, this new array of findings is primarily centered in the upper aerodigestive tract and cervical lymph nodes. What does omnicron COVID look like in medical imaging?

Unusual pattern on PET/CT may indicate COVID omicron variant

The Society of Nuclear Medicine and Molecular Imaging offered up a handful of tips to help providers who encounter such findings.

January 14, 2022

Around the web

Automated AI-generated measurements combined with annotated CT images can improve treatment planning and help referring physicians and patients better understand their disease, explained Sarah Jane Rinehart, MD, director of cardiac imaging with Charleston Area Medical Center.

Two advanced algorithms—one for CAC scores and another for segmenting cardiac chamber volumes—outperformed radiologists when assessing low-dose chest CT scans. 

"Gen AI can help tackle repetitive tasks and provide insights into massive datasets, saving valuable time," Thomas Kurian, CEO of Google Cloud, said Tuesday. 

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