Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Breakthrough method may improve cost, efficiency of radioisotope production

The approach uses a linear electron accelerator and naturally-occurring molybdenum-100, eliminating the need for a nuclear reactor or enriched uranium.

June 6, 2019

SHINE gains exclusive license for Lu-177 radioisotope production

Janesville, Wisconsin-based SHINE Medical Technologies has announced an agreement with the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), gaining exclusive rights over an innovation to produce lutetium-177 (Lu-177).

May 16, 2019

Novel imaging agent utilizes protein found in scorpion venom

Researchers have combined a new imaging technique and imaging agent which utilizes a synthesized amino acid found in scorpion venom to help illuminate brain tumors during surgery.

May 10, 2019

US Nuclear Regulatory Commission seeks feedback on radiopharmaceutical training requirements

The U.S. Nuclear Regulatory Commission (NRC) opened a 30-day public comment period seeking feedback on its draft document outlining training and experience requirements for administrating radiopharmaceuticals requiring a written directive.

May 8, 2019
Driven by its strategic goal to advance equity in the U.S. healthcare innovation sector, the American Medical Association (AMA) recently announced an initiative that supports leading industry stakeholders in committing to equitable health innovation opportunities targeted to improving health outcomes in historically marginalized communities. #Healthdisparities 

Radionuclide therapy shows long-term benefit in patients with neuroendocrine tumors

Peptide radionuclide therapy (PRRT) demonstrated long-term effectiveness in patients with malignant neuroendocrine tumors, reported authors of a study published in the Journal of Nuclear Medicine.

May 3, 2019
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Medical societies publish consensus document on iodine-131 therapy in thyroid cancer

The joint statement—published in Thyroid—was put out by American Thyroid Association, the European Association of Nuclear Medicine, the Society of Nuclear Medicine and Molecular Imaging and the European Thyroid Association.

May 3, 2019

PET study shows promise for treating lethal brain cancers

Johns Hopkin’s researchers have created a PET-based approach that can direct cancer drugs to precise points in the brains of mice, according to a study published in the May 1 edition of the Journal of Nuclear Medicine. If proven effective in humans, the researchers believe their technique could help patients with difficult brain tumors, such as glioblastomas.

May 1, 2019

Another study confirms 68Ga-PSMA-11 PET’s important role in prostate cancer care

The prospective single-center study, published April 30 in the American Journal of Roentgenology, adds more weight to the growing literature suggesting PSMA-11’s vital role in prostate cancer management.

 

May 1, 2019

Around the web

Automated AI-generated measurements combined with annotated CT images can improve treatment planning and help referring physicians and patients better understand their disease, explained Sarah Jane Rinehart, MD, director of cardiac imaging with Charleston Area Medical Center.

Two advanced algorithms—one for CAC scores and another for segmenting cardiac chamber volumes—outperformed radiologists when assessing low-dose chest CT scans. 

"Gen AI can help tackle repetitive tasks and provide insights into massive datasets, saving valuable time," Thomas Kurian, CEO of Google Cloud, said Tuesday. 

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